Visual Studio provides tools for deploying applications to a Web server. These tools provide an advantage over simply copying files, in that they handle any issues with registration and configuration automatically. However, you can copy the files and register them manually.
Micro Focus COBOL applications deployed to environment such as ASP.NET/Network drives are currently required to have full trust. Applications that are executed without full trust will cause a SecurityException and terminate. Full trust can be configured by using web.config (for ASP.NET) or by using your machines .NET Framework Configuration utility.
Because of the inherent risks that come with running in Full trust mode Microsoft recommends that the ASP.NET applications are isolated. This means that every Web site using COBOL should uses its own application pool and its own application pool identity to cut down the security exposure of executing the application with full trust.
For more information, see the MSDN: