Rumba+ operates on PCs with the following operating systems, applications, and environments:
- Windows 7, 8.1 , and 10, excluding Windows 10 releases 1507 and 1511
- Windows Server 2008 and 2012 R2
- Windows Terminal Server (WTS)
- Citrix XenApp (formerly Presentation Server)
- Microsoft Application Virtualization (APP-V)