Although you can't directly debug a COBOL application that is running in Enterprise Developer Build Tools for Windows it is a straightforward process to use Enterprise Developer to remotely debug an application that is running on Enterprise Developer Build Tools for Windows.
See Remote Debugging of Native COBOL Applications for detailed information on how to set up remote debugging, how to debug remotely, and how to resolve issues that sometimes occur when using remote debugging. In addition, Tutorial: Debugging COBOL Applications Remotely provides a step-by-step tutorial showing how to use Enterprise Developer running on one machine to debug a COBOL application that is running on a second machine.